
N-piperidine Ibrutinib
CAS No. 330785-90-5
N-piperidine Ibrutinib ( —— )
产品货号. M28669 CAS No. 330785-90-5
N-piperidine Ibrutinib 是一种有效的 BTK 抑制剂,WT BTK 的 IC50 值分别为 51.0,C481S BTK 的 IC50 值分别为 30.7 nM。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2722 | 有现货 |
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10MG | ¥3993 | 有现货 |
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25MG | ¥6399 | 有现货 |
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50MG | ¥9072 | 有现货 |
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100MG | ¥12069 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称N-piperidine Ibrutinib
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述N-piperidine Ibrutinib 是一种有效的 BTK 抑制剂,WT BTK 的 IC50 值分别为 51.0,C481S BTK 的 IC50 值分别为 30.7 nM。
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产品描述N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.(In Vitro):N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs. SJF638, SJF678, and SJF608 are potent PROTAC BTK degraders with DC50s of 374, 162, and 8.3 nM, respectively.
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体外实验——
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体内实验——
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同义词——
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通路Tyrosine Kinase
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靶点BTK
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受体Nrf2
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研究领域——
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适应症——
化学信息
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CAS Number330785-90-5
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分子量386.45
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分子式C22H22N6O
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纯度>98% (HPLC)
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溶解度——
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SMILESNc1c(c(-c(cc2)ccc2Oc2ccccc2)nn2C3CCNCC3)c2ncn1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chen H, et, al. Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. Mol Nutr Food Res. 2013 May;57(5):865-76.